Endocrine Abstracts

In our centre we use CNB for routine study of thyroid nodules since 2005. Four diagnostic categories for CNB’s results have been standardised: insufficient; benign; follicular proliferation (FOL), including follicular and oncocytic neoplasms; and malignant. Diagnosis of FOL was defined according to the presence of microfollicular patterned biopsies with scant or absent colloid, sometimes with minimal pleomorphism or discrete nuclear changes. This category could be equival...

In our centre, thyroid core-biopsy (CB) has replaced fine needle aspiration biopsy (FNAB) in the study of thyroid nodules because its better accuracy. International guidelines recommend repeating the FNA in cases of inadequate or insufficient first specimen, but nothing is published about the case in failed CB.Objective: To study the differences between nodules with inadequate and diagnostic thyroid Core Biopsy and the accuracy of repeating a CB after a ...

Fine-needle aspiration cytology (FNAC) remains the mainstay in the study of thyroid nodules, with cytologic adequate specimens in almost 85% of cases in expert hands. Apart from the limitation of inadequate samples, there are false negative diagnoses in some cases, particularly in larger (>3 cm) nodules. Considering this, Large-needle biopsy (LNB) could be useful to improve diagnostic precision. We review the pathology reports (PR) of more than 100 patients operated since ...

Introduction: To date, benign thyroid nodules complainig of symptomatic or cosmetic problems and autonomous functioning thyroid nodules (AFTN) have generally been treated with surgery or I131. Radiofrequency ablation (RFA) is a novel technique that has demonstrated safety and efficacy in the treatment of these nodules. We describe the clinical experience at our hospital.Material and method: We include 33 patients (28 women, 5 men) from January 2013 to Se...

Current guidelines suggest sonographic follow-up in thyroid nodules smaller than 10 mm with intermediate or highly suspicious features as ultrasound-guided FNAC has poor results in these nodules, and the risk of non-diagnosed thyroid carcinoma is very low. CNB has proved superior to repeated FNAC in case of insufficient or indeterminate first FNAC.Objective: Evaluate diagnostic accuracy of CNB in nodules smaller than 10 mm with intermediate or high suspi...

CNB is increasingly being used as a diagnostic test for thyroid nodules with an inadequate (Bethesda 1) or indeterminate (Bethesda 3 and 4) FNAC results, which can account for up to 30% of the samples in some studies. CNB, using larger specimens and histological sections rather than cytological samples, allows better definition. We propose a simplified four-tiered classification of CNB specimens instead of the Bethesda system and evaluate its efficiency compared to definitive ...